A sytematic review (SR) is a well structured review of literature that focuses on a specific topic while adhering to strict standards. A well constructed SR identifies, selects, assesses and synthesis relevant bodies of research in a tightly structured manner. The goal of the SR is to answer a predertermined specific clinical question (PICO) based on all available information and data and present this answer in a balance and unbiased conclsion. It is essential the SR be transparent, non-biased, duplicatable and clear in the final report. SRs must also be "objective, scientifically valid, and consistent."
|
P |
I |
C |
O |
|
Patient, Population, or Problem |
Intervention |
Comparison |
Outcome |
|
What are the characteristics of the patient or population |
What do you want to do with this patient (e.g. treat, diagnose, observe)? |
What is the alternative to the intervention (e.g. placebo, different drug, surgery)? |
What are the relevant outcomes (e.g. morbidity, death, complications)? |
RefWorks is a citation management software that is free to TCU students, faculty and staff. With RefWorks, you can: import references directly from multiple databases; organize and manage references; and format bibliographies and manuscripts.
AHRQ's Systematic Review Data Repository The Systematic Review Data Repository (SRDR) is a powerful and easy-to-use tool for the extraction and management of data for systematic review or meta-analysis. It is also an open and searchable archive of systematic reviews and their data.
DistilerSR DistillerSR is an online application designed specifically for the screening and data extraction phases of a systematic review. Subscription Fee. Additional technical information at: http://www.tectutorials.com/TERDistillerSR.htm
Step 1: Initiate the process (develop PICO), organize your team, develop a search strategy that minimizes bias and conflict of interests
Step 2: Develop the process for literature review: procedures, keywords
Step 3: Locate and screen studies for review as per agreed upon procedure
Step 4: Appraise any bias or conflict of interest in the studies and extract the data for analysis
Step 5: Summarize findings and asses body of evidence
Step 6: Prepare final report and proceed with peer review.
Reference: Eden, J.; Levit, L.; Berg, A.; & Morton, S. (Eds.) (2015). Finding what worked in health care: Standards for systematic reviews. Washington D.C.: The National Academies Press. Retrieved from http://www.nap.edu/openbook.php?record_id=13059&page=R1
Cochrane Handbook for Systematic Reviews of Interventions
Campbell Collaboration: Producing a Review
Finding What Works in Health Care: Standards for Systematic Reviews
AHRQ: Methods Guide for Effectiveness and Comparative Effectiveness Review
Systematic Reviews: CRD's Guidance for Undertaking Reviews in Health Care
